Detalhe da pesquisa
1.
Real-time measurements of ATP dynamics via ATeams in Plasmodium falciparum reveal drug-class-specific response patterns.
Antimicrob Agents Chemother
; 68(5): e0169023, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38501806
2.
Structure of Leishmania donovani 6-Phosphogluconate Dehydrogenase and Inhibition by Phosphine Gold(I) Complexes: A Potential Approach to Leishmaniasis Treatment.
Int J Mol Sci
; 24(10)2023 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37239962
3.
Structural Analysis of Plasmodium falciparum Hexokinase Provides Novel Information about Catalysis Due to a Plasmodium-Specific Insertion.
Int J Mol Sci
; 24(16)2023 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37628920
4.
An Optimized Dihydrodibenzothiazepine Lead Compound (SBI-0797750) as a Potent and Selective Inhibitor of Plasmodium falciparum and P. vivax Glucose 6-Phosphate Dehydrogenase 6-Phosphogluconolactonase.
Antimicrob Agents Chemother
; 66(4): e0210921, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35266827
5.
Glucose 6-phosphate dehydrogenase 6-phosphogluconolactonase: characterization of the Plasmodium vivax enzyme and inhibitor studies.
Malar J
; 18(1): 22, 2019 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30683097
6.
Benzo[b]quinolizinium Derivatives Have a Strong Antimalarial Activity and Inhibit Indoleamine Dioxygenase.
Antimicrob Agents Chemother
; 60(1): 115-25, 2016 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26459907
7.
Real-time imaging of the intracellular glutathione redox potential in the malaria parasite Plasmodium falciparum.
PLoS Pathog
; 9(12): e1003782, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24348249
8.
Atomic resolution crystal structure of glutaredoxin 1 from Plasmodium falciparum and comparison with other glutaredoxins.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 1): 91-100, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24419382
9.
Characterization of tryptophan aminotransferase 1 of Malassezia furfur, the key enzyme in the production of indolic compounds by M. furfur.
Exp Dermatol
; 22(11): 736-41, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24118363
10.
Identification and characterisation of the tegument-expressed aldehyde dehydrogenase SmALDH_312 of Schistosoma mansoni, a target of disulfiram.
Eur J Med Chem
; 251: 115179, 2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36948075
11.
Compartmentation of redox metabolism in malaria parasites.
PLoS Pathog
; 6(12): e1001242, 2010 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21203490
12.
Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase: a unique bifunctional enzyme from Plasmodium falciparum.
Biochem J
; 436(3): 641-50, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21443518
13.
The malarial parasite Plasmodium falciparum imports the human protein peroxiredoxin 2 for peroxide detoxification.
Proc Natl Acad Sci U S A
; 106(32): 13323-8, 2009 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19666612
14.
Prominent role of cysteine residues C49 and C343 in regulating Plasmodium falciparum pyruvate kinase activity.
Structure
; 30(10): 1452-1461.e3, 2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35998635
15.
Crystal structure of plasmoredoxin, a redox-active protein unique for malaria parasites.
Curr Res Struct Biol
; 4: 87-95, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35434650
16.
Crystal structure of Leishmania donovani glucose 6-phosphate dehydrogenase reveals a unique N-terminal domain.
Commun Biol
; 5(1): 1353, 2022 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36494598
17.
Characterization of Plasmodium falciparum macrophage migration inhibitory factor homologue and its cysteine deficient mutants.
Parasitol Int
; 87: 102513, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-34785370
18.
Structure and Function of Redox-Sensitive Superfolder Green Fluorescent Protein Variant.
Antioxid Redox Signal
; 37(1-3): 1-18, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35072524
19.
Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target.
Cell Rep
; 39(11): 110923, 2022 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35705035
20.
Molecular genetics evidence for the in vivo roles of the two major NADPH-dependent disulfide reductases in the malaria parasite.
J Biol Chem
; 285(48): 37388-95, 2010 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20852334